The increased application of drugs during the COVID-19 pandemic has resulted in their increased concentration in wastewater. Conventional wastewater treatment plants do not remove such pollutants effectively. Adsorption is a cheap, effective, and environmentally friendly method that can accomplish this. On the other hand, maintaining organic waste is required. Thus, in this study, plant waste-derived pelletized biochar obtained from different feedstock and pyrolyzed at 600 °C was applied for the adsorption of nitazoxanide, an antiparasitic drug used for the treatment of SARS-CoV-2. The adsorption was fast and enables one to remove the drug in one hour. The highest adsorption capacity was noted for biochar obtained from biogas production (14 mg/g). The process of NTZ adsorption was governed by chemisorption (k2 = 0.2371 g/mg min). The presence of inorganic ions had a detrimental effect on adsorption (Cl−, NO3− in 20–30%) and carbonates were the most effective in hindering the process (60%). The environmentally relevant concentration of DOM (10 mg/L) did not affect the process. The model studies were supported by the results with a real wastewater effluent (15% reduction). Depending on the applied feedstock, various models described nitazoxanide adsorption onto tested biochars. In summary, the application of carbonaceous adsorbents in the pelletized form is effective in nitazoxanide adsorption.