The aim of this research was to determine the effect of the addition of lupine flour (LF) on the values of the glycemic index (GI) and glycemic load (GL), physicochemical properties, and cooking quality of durum semolina pasta. The pasta was enriched with 0–25% of lupine flour (LF0‐LF25). Additionally, 7.5 and 20% of oat β‐glucans, 5% of vital gluten, and 20% of millet flour were used in a selected sample. The addition of 7.5% β‐glucans and 5% vital gluten to the product resulted in only a slight decrease in the GI of the products. A significant decrease in pasta GI was noted after the addition of 20% of lupine flour. The product enriched with 20% of lupine flour, 20% of β‐glucans, and 20% of millet flour had the lowest glycemic index and glycemic load (GI = 3.75%, GL = 7.2%, respectively). At the same time, the lupine‐flour‐enriched products were characterized by an increased concentration of protein, fat, ash, and dietary fiber. The addition of lupine flour at the level of up to 20% yielded functional products characterized by good cooking quality.